Handbook Of Mouse Mutations With Skin And Hair Abnormalities

Author : John P. Sundberg
Publisher : CRC Press
ISBN 13 : 1000142329
Total Pages : 582 pages
Book Rating : 4.27/5 ( download)

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Download or read book Handbook of Mouse Mutations with Skin and Hair Abnormalities written by John P. Sundberg and published by CRC Press. This book was released on 2020-08-26 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.

Author :
Publisher : Elsevier
ISBN 13 : 0080469078
Total Pages : 829 pages
Book Rating : 4.72/5 ( download)

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Download or read book The Mouse in Biomedical Research written by and published by Elsevier. This book was released on 2006-12-15 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse’s normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Author : Hans Hedrich
Publisher : Academic Press
ISBN 13 : 012382009X
Total Pages : 868 pages
Book Rating : 4.99/5 ( download)

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Download or read book The Laboratory Mouse written by Hans Hedrich and published by Academic Press. This book was released on 2012-06-14 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

Author : John P. Sundberg
Publisher : CRC Press
ISBN 13 : 1420049488
Total Pages : 216 pages
Book Rating : 4.80/5 ( download)

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Download or read book Systematic Approach to Evaluation of Mouse Mutations written by John P. Sundberg and published by CRC Press. This book was released on 1999-07-23 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. Systematic Approach to Evaluation of Mouse Mutations includes information on medical photography, grafting procedures, how to map the genes and evaluate the special biological characte

Author : Eric C. Holland
Publisher : John Wiley & Sons
ISBN 13 : 047144460X
Total Pages : 504 pages
Book Rating : 4.02/5 ( download)

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Download or read book Mouse Models of Human Cancer written by Eric C. Holland and published by John Wiley & Sons. This book was released on 2004-08-27 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mice have become the species of choice for modeling the complex interactions between tumor cells and the host environment. Mouse genetics are easily manipulated, and a growing array of technology exists for this purpose. Mouse models allow investigators to better understand causal relationships between specific genetic alterations and tumors, utilize new imaging techniques, and test novel therapies. Recent developments along these lines show great promise for the development of new anti-cancer treatments. Mouse Models of Human Cancer provides researchers and students with a complete resource on the subject, systematically presenting the principles, methodologies, applications, and challenges associated with this exciting field. Offering a survey of the latest research and a description of future areas of interest, this text: Presents real experimental data Describes organ site-specific mouse models Clearly identifies suitable models for further drug testing Critically analyzes current methodologies and their limitations Features numerous recognizable expert contributors Lists key Web sites, reagents, and companies From mouse handling and genetic engineering to preclinical trials, Mouse Models of Human Cancer is a comprehensive guide to using these models and relating them to human disease. Its uniform presentation describes organ-specific models in clinical, imaging, and molecular terms, and lays out the relevant genetics, experimental approaches, histological comparisons with human disease, and conclusions. Combining stellar chapter authors, rich illustrations, and clear, up-to-date coverage, Mouse Models of Human Cancer is an invaluable resource for advanced students and cutting-edge researchers.

Author : John P. Sundberg
Publisher : John Wiley & Sons
ISBN 13 : 1119624576
Total Pages : 564 pages
Book Rating : 4.78/5 ( download)

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Download or read book Pathology of Genetically Engineered and Other Mutant Mice written by John P. Sundberg and published by John Wiley & Sons. This book was released on 2022-01-26 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. Readers will also benefit from: A thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice An exploration of concepts related to validating animal models, including the Cinderella Effect Practical discussions of basic necropsy methods and grading lesions for computational analyses Concise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.

Author :
Publisher :
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.15/5 ( download)

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Download or read book Comparative Pathology Bulletin written by and published by . This book was released on 1992 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Brian J. Nickoloff
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805583915
Total Pages : 391 pages
Book Rating : 4.16/5 ( download)

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Download or read book Dermatologic Immunity written by Brian J. Nickoloff and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nickeloff (skin cancer research, Cardinal Bernardin Cancer Center, Chicago) and Nestle (cutaneous medicine and immunotherapy, King's College, London School of Medicine at Guy's, UK) assemble 19 review articles on autoimmune disease processes that affect the skin, covering both humoral and cellular immunity. The etiology, cellular and molecular mechanisms, therapeutic strategies, and pathophysiology of diseases such as psoriasis, dermatitis, cutaneous lupus erythematosus, vitiligo, and scleroderma are discussed by individuals in dermatology, genetics, immunology, and pathology who are based around the world. The book is aimed at clinical researchers, students, allergists, immunologists, dermatologists, and internists.

Author : Piper M. Treuting
Publisher : Academic Press
ISBN 13 : 0128029196
Total Pages : 570 pages
Book Rating : 4.90/5 ( download)

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Download or read book Comparative Anatomy and Histology written by Piper M. Treuting and published by Academic Press. This book was released on 2017-08-29 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease. Offers the only comprehensive source for comparing mouse, rat, and human anatomy and histology through over 1500 full-color images, in one reference work Enables human and veterinary pathologists to examine tissue samples with greater accuracy and confidence Teaches biomedical researchers to examine the histologic changes in their model rodents Experts from both human and veterinary fields take readers through each organ system in a side-by-side comparative approach to anatomy and histology - human Netter anatomy images along with Netter-style rodent images

Author : Ulrich Mohr
Publisher : International Life Sciences Institute/I L S I Press
ISBN 13 :
Total Pages : 532 pages
Book Rating : 4.77/5 ( download)

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Download or read book Pathobiology of the Aging Mouse: Nervous system, special senses (eye and ear), digestive system, integumentary system and mammary gland, and musculoskeletal system written by Ulrich Mohr and published by International Life Sciences Institute/I L S I Press. This book was released on 1996 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: