Peptide Nucleic Acids Morpholinos And Related Antisense Biomolecules

Author : Christopher Janson
Publisher : Springer Science & Business Media
ISBN 13 : 0387329560
Total Pages : 286 pages
Book Rating : 4.67/5 ( download)

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Download or read book Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules written by Christopher Janson and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.

Author : Christopher Janson
Publisher : Springer
ISBN 13 : 9780387500218
Total Pages : 0 pages
Book Rating : 4.19/5 ( download)

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Download or read book Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules written by Christopher Janson and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.

Author : Christopher Janson
Publisher :
ISBN 13 : 9781587060649
Total Pages : pages
Book Rating : 4.47/5 ( download)

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Download or read book Peptide Nucleic Acids written by Christopher Janson and published by . This book was released on 2003-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Peter E. Nielsen
Publisher : Garland Science
ISBN 13 : 9780954523244
Total Pages : 332 pages
Book Rating : 4.45/5 ( download)

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Download or read book Peptide Nucleic Acids written by Peter E. Nielsen and published by Garland Science. This book was released on 2004 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide Nucleic Acids, Second Edition has been extensively revised, updated, and enlarged to contain many new chapters covering the most recent topics and applications in this fast-moving field. The book contains state-of-the-art protocols and applications on all aspects of peptide nucleic acids. Concepts are clearly explained with each chapter containing concise background information. Written by leading experts in the field, the book is an invaluable and complete reference work on this novel and exciting area.

Author : Joseph N. M. Mol
Publisher : CRC Press
ISBN 13 : 9780824785161
Total Pages : 256 pages
Book Rating : 4.69/5 ( download)

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Download or read book Antisense Nucleic Acids and Proteins written by Joseph N. M. Mol and published by CRC Press. This book was released on 1991-01-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of papers from many different scientific meetings in recent years, this reference source reviews the use of antisense nucleic acids to modulate or down-regulate gene expression, provides clues on the action mechanism of sense and antisense genes as well as data on antisense nucleic aci

Author : Eylon Yavin
Publisher :
ISBN 13 : 9783039368860
Total Pages : 154 pages
Book Rating : 4.69/5 ( download)

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Download or read book Peptide Nucleic Acids written by Eylon Yavin and published by . This book was released on 2020-09-10 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles four review articles and four research papers that highlight recent developments in the field of peptide nucleic acid (PNA) chemistry and biomedicine. The review articles encompass a variety of fields related to PNA, emphasizing the versatility of this DNA mimic. Two excellent reviews detail the use of PNA for molecular diagnostics of miRNAs and genetic point mutations (SNPs). Another review provides a comprehensive analysis of the various approaches for gene editing using chemically modified PNA molecules. Lastly, PNA molecules are elegantly described as effective (antisense) antimicrobial agents in the final review. The high binding affinity of PNA to complementary DNA and RNA is highlighted in three research articles. Two articles show how PNA molecules act as splice modulating and RNA masking molecules, separately. In another contribution, the high affinity and achiral characteristics of PNAs are used to developed a stable L-DNA-based catalytic hairpin assembly. Lastly, chemically-modified PNA molecules are shown to be superior probes for SNP detection. Altogether, these studies illustrate how PNA molecules may be useful for a variety of biomedical applications as either therapeutic or diagnostic agents.

Author : Roger L. Lundblad
Publisher : CRC Press
ISBN 13 : 1439849005
Total Pages : 426 pages
Book Rating : 4.02/5 ( download)

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Download or read book Chemical Modification of Biological Polymers written by Roger L. Lundblad and published by CRC Press. This book was released on 2016-04-19 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the chemical modification of biological polymers and the emerging applications of this technology, Chemical Modification of Biological Polymers reflects the change in emphasis in this subsection of biotechnology from the study of protein structure and function toward applications in therapeutics and diagnostics. Highlights The basic organic chemistry of the modification proteins, nucleic acids, oligosaccharides, polysaccharides, and their applications New analytical technologies used to characterize the chemical modification of biological polymers Identification of in vivo, non-enzymatic chemical modification of biological polymers Specific chemical modifications to generate biopharmaceutical products This book covers the basics on the organic chemistry underlying the chemical modification of biopolymers, including updates on the use of various chemical reagents. It describes the current status of chemical modification of biological polymers and emerging applications of this technology in biotechnology. These technologies are important for the manufacture of conjugate proteins used in drug delivery, for the preparation of nucleic acid microarrays, and for the preparation of hydrogels and other materials used in tissue engineering.

Author : Rachel K. Miller
Publisher : Springer
ISBN 13 : 3319514369
Total Pages : 372 pages
Book Rating : 4.69/5 ( download)

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Download or read book Kidney Development and Disease written by Rachel K. Miller and published by Springer. This book was released on 2017-04-13 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.

Author : Jens Kurreck
Publisher : Royal Society of Chemistry
ISBN 13 : 0854041168
Total Pages : 362 pages
Book Rating : 4.69/5 ( download)

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Download or read book Therapeutic Oligonucleotides written by Jens Kurreck and published by Royal Society of Chemistry. This book was released on 2008 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a compelling overall update on current status of RNA interference

Author : Sudhir Agrawal
Publisher : Springer Science & Business Media
ISBN 13 : 9783540638339
Total Pages : 664 pages
Book Rating : 4.34/5 ( download)

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Download or read book Antisense Research and Application written by Sudhir Agrawal and published by Springer Science & Business Media. This book was released on 1998-04-16 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts